Glial Cell Response: A Pathogenic Factor in Parkinson's Disease
نویسندگان
چکیده
منابع مشابه
کلون کردن cdnaیneurotrophic factor)gdnf(glial cell line-derived در حامل بیانی با قابلیت الحاق هدفمند در ژنوم سلول میزبان
چ فده قیقحت : هدننک دک یلاوت زا یپک ود یاراد ینایب روتکو تخاس هعلاطم نیا زا فده gdnf نایب یارب یناسنا .تسا نارادناتسپ یلولس هدر رد : قیقحت شور cds نیئتورپ gdnf صخشم یکیتامروفناویب تاعلاطم هلیسو هب یناسنا دیدرگ تفج ود کمک اب . اب هک یرمیارپ رازفا مرن oligo7.4 یحارط دندش رد هناشن دیتپپ ، n و نیئتورپ لانیمرت his-tag رد c نآ لانیمرت شور زا هدافتسا اب .تفرگ رارق t/a cloning روتکو رد هدش دی...
The Effects of Progesterone on Glial Cell Line-derived Neurotrophic Factor Secretion from C6 Glioma Cells
Objective(s)Progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. In recent years, the neuroprotective effects of progesterone have attracted growing interest. Glial cell line-derived neurotrophic factor (GDNF), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...
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A variety of inflammatOry proteins has been identified, particularly in thevicinity of /3-amyloid plaques, in the brain of patients INith Alzheimer'sdisease. Current findings indicate that these molecules are involved in anum?er of key steps in the parbological cascade. Activation products ofClasSICal complement pathway Clq, C4 and C3, but not the alternativepathway factor p...
متن کاملDose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys.
A double-blinded study was conducted to evaluate the dose response of hemiparkinsonian rhesus monkeys to intracerebroventricular (ICV) injections of recombinant methionine human glial cell line-derived neurotrophic factor (GDNF). Thirty rhesus monkeys with stable hemiparkinsonian features were divided into six treatment groups (vehicle, 10, 30, 100, 300 and 1000 microg GDNF; n = 5/group). Each ...
متن کاملincreased expression of glial cell line-derived neurotrophic factor in rat brain after traumatic brain injury
glial cell line-derived neurotrophic factor (gdnf) plays important roles not only for the differentiation of neurons during normal development but also for the survival and recovery of many populations of mature neurons. the effect of traumatic brain injury (tbi) on the expression of gdnf is currently unknown. to determine if there is alteration in gdnf after tbi we examined the effect of contr...
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ژورنال
عنوان ژورنال: Journal of Neurovirology
سال: 2002
ISSN: 1355-0284,1538-2443
DOI: 10.1080/13550280290100905